Surgical Treatment of Solid Pseudopapillary Tumor in Pediatric Patients: Two Case Reports and a Brief Narrative Review

Area of Science:

• Oncology
• Gastroenterology
• Pediatric Surgery

Background:

• Solid pseudopapillary neoplasms (SPNs) are rare cystic tumors of the pancreas.
• SPNs typically originate in the pancreas but can rarely occur in extrapancreatic locations.
• They constitute a small percentage of pancreatic neoplasms and a larger fraction of cystic pancreatic neoplasms.

Observation:

• This study presents two pediatric cases of SPNs in adolescent females (16 and 14 years old).
• Both patients were diagnosed and treated at the authors' center.
• Extrapancreatic locations for SPNs are exceedingly uncommon.

Findings:

• Surgical resection is confirmed as the primary treatment modality for SPNs.
• Wide margin surgery is crucial for effective disease management.
• Metastasectomy, when necessary, is an integral part of the surgical approach.

Implications:

• The findings reinforce the efficacy of surgical intervention for SPNs, even in pediatric cases.
• Aggressive surgical management, including margin-clearance and metastasis removal, is vital for long-term control.
• This case series contributes to understanding the management of rare pediatric SPNs.